Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar Functions

Age can be reset during mitosis in both yeast and stem cells to generate a young daughter cell from an aged and deteriorated one. This phenomenon requires asymmetry-generating genes (AGGs) that govern the asymmetrical inheritance of aggregated proteins. Using a genome-wide imaging screen to identify...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Hill, Sandra Malmgren, Hao, Xinxin, Grönvall, Johan, Spikings-Nordby, Stephanie, Widlund, Per O., Amen, Triana, Jörhov, Anna, Josefson, Rebecca, Kaganovich, Daniel, Liu, Beidong, Nyström, Thomas
Format: Artigo
Language:Inglês
Published: Cell Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963537/
https://ncbi.nlm.nih.gov/pubmed/27373154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.016
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