Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein Aggregates

Sir2 is a central regulator of yeast aging and its deficiency increases daughter cell inheritance of stress- and aging-induced misfolded proteins deposited in aggregates and inclusion bodies. Here, by quantifying traits predicted to affect aggregate inheritance in a passive manner, we found that a p...

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Detalhes bibliográficos
Main Authors: Song, Jia, Yang, Qian, Yang, Junsheng, Larsson, Lisa, Hao, Xinxin, Zhu, Xuefeng, Malmgren-Hill, Sandra, Cvijovic, Marija, Fernandez-Rodriguez, Julia, Grantham, Julie, Gustafsson, Claes M., Liu, Beidong, Nyström, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117435/
https://ncbi.nlm.nih.gov/pubmed/25079602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004539
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