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Axial contraction and short-range compaction of chromatin synergistically promote mitotic chromosome condensation

The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units of manageable size for the mitotic spindle. Here, we report on how phosphorylation at serine 10 of histone H3 (H3 S10) contributes to this process. Using a fluorescence-based assay to study local com...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kruitwagen, Tom, Denoth-Lippuner, Annina, Wilkins, Bryan J, Neumann, Heinz, Barral, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755758/
https://ncbi.nlm.nih.gov/pubmed/26615018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10396
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