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Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins

During mitosis, chromosomes are highly condensed and transcription is silenced globally. One explanation for transcriptional repression is the reduced accessibility of transcription factors. To directly test this hypothesis and to investigate the dynamics of mitotic chromatin, we evaluate the exchan...

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Bibliografiske detaljer
Main Authors: Chen, Danyang, Dundr, Miroslav, Wang, Chen, Leung, Anthony, Lamond, Angus, Misteli, Tom, Huang, Sui
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171683/
https://ncbi.nlm.nih.gov/pubmed/15623580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407182
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