Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins

During mitosis, chromosomes are highly condensed and transcription is silenced globally. One explanation for transcriptional repression is the reduced accessibility of transcription factors. To directly test this hypothesis and to investigate the dynamics of mitotic chromatin, we evaluate the exchan...

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Bibliographic Details
Main Authors: Chen, Danyang, Dundr, Miroslav, Wang, Chen, Leung, Anthony, Lamond, Angus, Misteli, Tom, Huang, Sui
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171683/
https://ncbi.nlm.nih.gov/pubmed/15623580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407182
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