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Slow chromatin dynamics enhances promoter accessibility to transcriptional condensates

Enhancers are DNA sequences at a long genomic distance from target genes. Recent experiments suggest that enhancers are anchored to the surfaces of condensates of transcription machinery and that the loop extrusion process enhances the transcription level of their target genes. Here, we theoreticall...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yamamoto, Tetsuya, Sakaue, Takahiro, Schiessel, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136786/
https://ncbi.nlm.nih.gov/pubmed/33885786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab275
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