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Slow chromatin dynamics enhances promoter accessibility to transcriptional condensates

Enhancers are DNA sequences at a long genomic distance from target genes. Recent experiments suggest that enhancers are anchored to the surfaces of condensates of transcription machinery and that the loop extrusion process enhances the transcription level of their target genes. Here, we theoreticall...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Yamamoto, Tetsuya, Sakaue, Takahiro, Schiessel, Helmut
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8136786/
https://ncbi.nlm.nih.gov/pubmed/33885786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab275
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