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Chromatin condensation fluctuations rather than steady-state predict chromatin accessibility

Chromatin accessibility to protein factors is critical for genome activities. However, the dynamic properties of chromatin higher-order structures that regulate its accessibility are poorly understood. Here, we took advantage of the microenvironment sensitivity of the fluorescence lifetime of EGFP-H...

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Publicat a:Nucleic Acids Res
Autors principals: Audugé, Nicolas, Padilla-Parra, Sergi, Tramier, Marc, Borghi, Nicolas, Coppey-Moisan, Maïté
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614833/
https://ncbi.nlm.nih.gov/pubmed/31081027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz373
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