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Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing

In eukaryotes, intra-chromosomal recombination generates DNA circles, but little is known about how cells react to them. In yeast, partitioning of such circles to the mother cell at mitosis ensures their loss from the population but promotes replicative ageing. Nevertheless, the mechanisms of partit...

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Veröffentlicht in:eLife
Hauptverfasser: Denoth-Lippuner, Annina, Krzyzanowski, Marek Konrad, Stober, Catherine, Barral, Yves
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232608/
https://ncbi.nlm.nih.gov/pubmed/25402830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03790
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