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Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing

In eukaryotes, intra-chromosomal recombination generates DNA circles, but little is known about how cells react to them. In yeast, partitioning of such circles to the mother cell at mitosis ensures their loss from the population but promotes replicative ageing. Nevertheless, the mechanisms of partit...

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Bibliographic Details
Published in:eLife
Main Authors: Denoth-Lippuner, Annina, Krzyzanowski, Marek Konrad, Stober, Catherine, Barral, Yves
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232608/
https://ncbi.nlm.nih.gov/pubmed/25402830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03790
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