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Asymmetric partitioning of transfected DNA during mammalian cell division

Foreign DNA molecules and chromosomal fragments are generally eliminated from proliferating cells, but we know little about how mammalian cells prevent their propagation. Here, we show that dividing human and canine cells partition transfected plasmid DNA asymmetrically, preferentially into the daug...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wang, Xuan, Le, Nhung, Denoth-Lippuner, Annina, Barral, Yves, Kroschewski, Ruth
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932973/
https://ncbi.nlm.nih.gov/pubmed/27298340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606091113
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