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A Presenilin-2–ARF4 trafficking axis modulates Notch signaling during epidermal differentiation

How primary cilia impact epidermal growth and differentiation during embryogenesis is poorly understood. Here, we show that during skin development, Notch signaling occurs within the ciliated, differentiating cells of the first few suprabasal epidermal layers. Moreover, both Notch signaling and cili...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Ezratty, Ellen J., Pasolli, H. Amalia, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932368/
https://ncbi.nlm.nih.gov/pubmed/27354375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508082
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