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A Presenilin-2–ARF4 trafficking axis modulates Notch signaling during epidermal differentiation
How primary cilia impact epidermal growth and differentiation during embryogenesis is poorly understood. Here, we show that during skin development, Notch signaling occurs within the ciliated, differentiating cells of the first few suprabasal epidermal layers. Moreover, both Notch signaling and cili...
Guardat en:
| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932368/ https://ncbi.nlm.nih.gov/pubmed/27354375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508082 |
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