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AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis

The mechanisms by which mammalian epidermal stem cells cease to proliferate and embark upon terminal differentiation are still poorly understood. By conditionally ablating two highly expressed transcription factors, AP-2α and AP-2γ, we unmasked functional redundancies and discovered an essential rol...

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Detalhes bibliográficos
Main Authors: Wang, Xuan, Pasolli, H. Amalia, Williams, Trevor, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2557040/
https://ncbi.nlm.nih.gov/pubmed/18824566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804030
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