Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program

In general, cell fate is determined primarily by transcription factors, followed by epigenetic mechanisms fixing the status. While the importance of transcription factors controlling cell fate has been well characterized, epigenetic regulation of cell fate maintenance remains to be elucidated. Here...

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Publicado en:Genes Dev
Autores principales: Ikawa, Tomokatsu, Masuda, Kyoko, Endo, Takaho A., Endo, Mitsuhiro, Isono, Kyoichi, Koseki, Yoko, Nakagawa, Rinako, Kometani, Kohei, Takano, Junichiro, Agata, Yasutoshi, Katsura, Yoshimoto, Kurosaki, Tomohiro, Vidal, Miguel, Koseki, Haruhiko, Kawamoto, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159663/
https://ncbi.nlm.nih.gov/pubmed/27913604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.290593.116
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