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Multi‐arm group sequential designs with a simultaneous stopping rule

Multi‐arm group sequential clinical trials are efficient designs to compare multiple treatments to a control. They allow one to test for treatment effects already in interim analyses and can have a lower average sample number than fixed sample designs. Their operating characteristics depend on the s...

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Bibliografski detalji
Izdano u:Stat Med
Glavni autori: Urach, S., Posch, M.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157767/
https://ncbi.nlm.nih.gov/pubmed/27550822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7077
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