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Efficient Adaptive Randomization and Stopping Rules in Multi-arm Clinical Trials for Testing a New Treatment
Motivated by applications to confirmatory clinical trials for testing a new treatment against a placebo or active control when the new treatment has k possible treatment strategies (arms)—for example, k possible doses for a new drug—we develop an asymptotic theory for efficient outcome-adaptive rand...
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| Gepubliceerd in: | Seq Anal |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476492/ https://ncbi.nlm.nih.gov/pubmed/26109746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07474946.2012.719433 |
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