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Group Sequential Designs for Developing and Testing Biomarker-guided Personalized Therapies in Comparative Effectiveness Research
Biomarker-guided personalized therapies offer great promise to improve drug development and improve patient care, but also pose difficult challenges in designing clinical trials for the development and validation of these therapies. We first give a review of the existing approaches, briefly for clin...
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| Publicado no: | Contemp Clin Trials |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364679/ https://ncbi.nlm.nih.gov/pubmed/23994669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2013.08.007 |
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