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Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains

Molecular details of the recognition of disordered antigens by their cognate antibodies have not been studied as extensively as folded protein antigens and much is still unknown. To follow the conformational changes in the antibody and cross-talk between its subunits and with antigens, we performed...

詳細記述

保存先:
書誌詳細
出版年:Protein Eng Des Sel
主要な著者: Zhao, Jun, Nussinov, Ruth, Ma, Buyong
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157118/
https://ncbi.nlm.nih.gov/pubmed/27899437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw065
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