Llwytho...

Druggable Orthosteric and Allosteric Hot Spots to Target Protein-protein Interactions

Drug designing targeting protein-protein interactions is challenging. Because structural elucidation and computational analysis have revealed the importance of hot spot residues in stabilizing these interactions, there have been on-going efforts to develop drugs which bind the hot spots and out-comp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Pharm Des
Prif Awduron: Ma, Buyong, Nussinov, Ruth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361532/
https://ncbi.nlm.nih.gov/pubmed/23713780
Tagiau: Ychwanegu Tag
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