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The Different Ways through Which Specificity Works in Orthosteric and Allosteric Drugs

Currently, there are two types of drugs on the market: orthosteric, which bind at the active site; and allosteric, which bind elsewhere on the protein surface, and allosterically change the conformation of the protein binding site. In this perspective we argue that the different mechanisms through w...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Curr Pharm Des
Päätekijät: Nussinov, Ruth, Tsai, Chung-Jung
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458136/
https://ncbi.nlm.nih.gov/pubmed/22316155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138161212799436377
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