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Gene-specific transcription activation via long-range allosteric shape-shifting

How is specificity transmitted over long distances at the molecular level? REs (regulatory elements) are often far from transcription start sites. In the present review we discuss possible mechanisms to explain how information from specific REs is conveyed to the basal transcription machinery throug...

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Bibliografiske detaljer
Udgivet i:Biochem J
Main Authors: Tsai, Chung-Jung, Nussinov, Ruth
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7385929/
https://ncbi.nlm.nih.gov/pubmed/21916844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110972
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