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How Similar Are Protein Folding and Protein Binding Nuclei? Examination of Vibrational Motions of Energy Hot Spots and Conserved Residues

The underlying physico-chemical principles of the interactions between domains in protein folding are similar to those between protein molecules in binding. Here we show that conserved residues and experimental hot spots at intermolecular binding interfaces overlap residues that vibrate with high fr...

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Detalhes bibliográficos
Main Authors: Haliloglu, Turkan, Keskin, Ozlem, Ma, Buyong, Nussinov, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305212/
https://ncbi.nlm.nih.gov/pubmed/15596504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051342
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