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How Similar Are Protein Folding and Protein Binding Nuclei? Examination of Vibrational Motions of Energy Hot Spots and Conserved Residues

The underlying physico-chemical principles of the interactions between domains in protein folding are similar to those between protein molecules in binding. Here we show that conserved residues and experimental hot spots at intermolecular binding interfaces overlap residues that vibrate with high fr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Haliloglu, Turkan, Keskin, Ozlem, Ma, Buyong, Nussinov, Ruth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305212/
https://ncbi.nlm.nih.gov/pubmed/15596504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051342
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