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How Similar Are Protein Folding and Protein Binding Nuclei? Examination of Vibrational Motions of Energy Hot Spots and Conserved Residues

The underlying physico-chemical principles of the interactions between domains in protein folding are similar to those between protein molecules in binding. Here we show that conserved residues and experimental hot spots at intermolecular binding interfaces overlap residues that vibrate with high fr...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Haliloglu, Turkan, Keskin, Ozlem, Ma, Buyong, Nussinov, Ruth
التنسيق: Artigo
اللغة:Inglês
منشور في: Biophysical Society 2005
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305212/
https://ncbi.nlm.nih.gov/pubmed/15596504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051342
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