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Hot Spots in a Network of Functional Sites
It is of significant interest to understand how proteins interact, which holds the key phenomenon in biological functions. Using dynamic fluctuations in high frequency modes, we show that the Gaussian Network Model (GNM) predicts hot spot residues with success rates ranging between S 8–58%, C 84–95%...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759471/ https://ncbi.nlm.nih.gov/pubmed/24023934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074320 |
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