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Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains
Molecular details of the recognition of disordered antigens by their cognate antibodies have not been studied as extensively as folded protein antigens and much is still unknown. To follow the conformational changes in the antibody and cross-talk between its subunits and with antigens, we performed...
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| Publicado no: | Protein Eng Des Sel |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5157118/ https://ncbi.nlm.nih.gov/pubmed/27899437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw065 |
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