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Antigen binding allosterically promotes Fc receptor recognition
A key question in immunology is whether antigen recognition and Fc receptor (FcR) binding are allosterically linked. This question is also relevant for therapeutic antibody design. Antibody Fab and Fc domains are connected by flexible unstructured hinge region. Fc chains have conserved glycosylation...
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| Publicado no: | MAbs |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6343797/ https://ncbi.nlm.nih.gov/pubmed/30212263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1522178 |
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