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Allosteric control of antibody-prion recognition through oxidation of a disulfide bond between the CH and CL chains

Molecular details of the recognition of disordered antigens by their cognate antibodies have not been studied as extensively as folded protein antigens and much is still unknown. To follow the conformational changes in the antibody and cross-talk between its subunits and with antigens, we performed...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Protein Eng Des Sel
Päätekijät: Zhao, Jun, Nussinov, Ruth, Ma, Buyong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157118/
https://ncbi.nlm.nih.gov/pubmed/27899437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw065
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