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Effect of Regulatory Element DNA Methylation on Tissue-Type Plasminogen Activator Gene Expression
Expression of the tissue-type plasminogen activator gene (t-PA; gene name PLAT) is regulated, in part, by epigenetic mechanisms. We investigated the relationship between PLAT methylation and PLAT expression in five primary human cell types and six transformed cell lines. CpG methylation was analyzed...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5156355/ https://ncbi.nlm.nih.gov/pubmed/27973546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167588 |
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