Effect of ATRA and ATO on the expression of tissue factor in NB4 acute promyelocytic leukemia cells and regulatory function of the inflammatory cytokines TNF and IL-1β

The characteristic hemorrhages of acute promyelocytic leukemia (APL) are caused in part by the high expression of tissue factor (TF) on leukemic cells, which also produce TNF and IL-1β, proinflammatory cytokines known to increase TF in various cell types. Exposure of NB4 cells, an APL cell line, to...

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Publicat a:Ann Hematol
Autors principals: Dunoyer-Geindre, Sylvie, Rivier-Cordey, Anne-Sophie, Tsopra, Olga, Lecompte, Thomas, Kruithof, Egbert K. O.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406437/
https://ncbi.nlm.nih.gov/pubmed/28343272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-017-2970-5
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