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Fluvastatin inhibits regulated secretion of endothelial cell von Willebrand factor in response to diverse secretagogues

Regulated secretion of EC (endothelial cell) vWF (von Willebrand factor) is part of the haemostatic response. It occurs in response to secretagogues that raise intracellular calcium or cAMP. Statins are cholesterol-lowering drugs used for the treatment of cardiovascular disease. We studied the effec...

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Detalhes bibliográficos
Main Authors: Fish, Richard J., Yang, Hong, Viglino, Christelle, Schorer, Raoul, Dunoyer-Geindre, Sylvie, Kruithof, Egbert K. O.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267313/
https://ncbi.nlm.nih.gov/pubmed/17472573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070404
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