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Secretion of von Willebrand factor by endothelial cells links sodium to hypercoagulability and thrombosis

Hypercoagulability increases risk of thrombi that cause cardiovascular events. Here we identify plasma sodium concentration as a factor that modulates blood coagulability by affecting the production of von Willebrand factor (vWF), a key initiator of the clotting cascade. We find that elevation of sa...

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Bibliographic Details
Main Authors: Dmitrieva, Natalia I., Burg, Maurice B.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035979/
https://ncbi.nlm.nih.gov/pubmed/24733925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404809111
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