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Secretion of von Willebrand factor by endothelial cells links sodium to hypercoagulability and thrombosis
Hypercoagulability increases risk of thrombi that cause cardiovascular events. Here we identify plasma sodium concentration as a factor that modulates blood coagulability by affecting the production of von Willebrand factor (vWF), a key initiator of the clotting cascade. We find that elevation of sa...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035979/ https://ncbi.nlm.nih.gov/pubmed/24733925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404809111 |
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