Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

Endothelial secretion of von Willebrand factor (VWF) from intracellular organelles known as Weibel-Palade bodies (WPBs) is required for platelet adhesion to the injured vessel wall. Here, we demonstrate that WPBs are in some cases found near or within autophagosomes and that endothelial autophagosom...

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Detalhes bibliográficos
Main Authors: Torisu, Takehiro, Torisu, Kumiko, Lee, In Hye, Liu, Jie, Malide, Daniela, Combs, Christian A., Wu, Xufeng S., Rovira, Ilsa I., Fergusson, Maria M., Weigert, Roberto, Connelly, Patricia S., Daniels, Mathew P, Komatsu, Masaaki, Cao, Liu, Finkel, Toren
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795899/
https://ncbi.nlm.nih.gov/pubmed/24056772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3288
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