Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

Endothelial secretion of von Willebrand factor (VWF) from intracellular organelles known as Weibel-Palade bodies (WPBs) is required for platelet adhesion to the injured vessel wall. Here, we demonstrate that WPBs are in some cases found near or within autophagosomes and that endothelial autophagosom...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Torisu, Takehiro, Torisu, Kumiko, Lee, In Hye, Liu, Jie, Malide, Daniela, Combs, Christian A., Wu, Xufeng S., Rovira, Ilsa I., Fergusson, Maria M., Weigert, Roberto, Connelly, Patricia S., Daniels, Mathew P, Komatsu, Masaaki, Cao, Liu, Finkel, Toren
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795899/
https://ncbi.nlm.nih.gov/pubmed/24056772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3288
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