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The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story
von Willebrand factor (VWF) plays key roles in both primary and secondary hemostasis by capturing platelets and chaperoning clotting factor VIII, respectively. It is stored within the Weibel–Palade bodies (WPBs) of endothelial cells as a highly prothrombotic protein, and its release is thus necessar...
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| Veröffentlicht in: | J Thromb Haemost |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255685/ https://ncbi.nlm.nih.gov/pubmed/23809123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12225 |
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