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The secretion of von Willebrand factor from endothelial cells; an increasingly complicated story

von Willebrand factor (VWF) plays key roles in both primary and secondary hemostasis by capturing platelets and chaperoning clotting factor VIII, respectively. It is stored within the Weibel–Palade bodies (WPBs) of endothelial cells as a highly prothrombotic protein, and its release is thus necessar...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Nightingale, T, Cutler, D
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255685/
https://ncbi.nlm.nih.gov/pubmed/23809123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12225
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