Gene conversion limits divergence of mammalian TLR1 and TLR6

BACKGROUND: Toll-like receptors (TLR) recognize pathogen-associated molecular patterns and are important mediators of the innate immune system. TLR1 and TLR6 are paralogs and located in tandem on the same chromosome in mammals. They form heterodimers with TLR2 and bind lipopeptide components of gram...

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Bibliographic Details
Main Authors: Kruithof, Egbert KO, Satta, Nathalie, Liu, Jia Wei, Dunoyer-Geindre, Sylvie, Fish, Richard J
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077338/
https://ncbi.nlm.nih.gov/pubmed/17727694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-148
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