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Hypoxia and defective apoptosis drive genomic instability and tumorigenesis
Genomic instability is a hallmark of cancer development and progression, and characterizing the stresses that create and the mechanisms by which cells respond to genomic perturbations is essential. Here we demonstrate that antiapoptotic BCL-2 family proteins promoted tumor formation of transformed b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515288/ https://ncbi.nlm.nih.gov/pubmed/15314031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1204904 |
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