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Tumor hypoxia as a driving force in genetic instability

Sub-regions of hypoxia exist within all tumors and the presence of intratumoral hypoxia has an adverse impact on patient prognosis. Tumor hypoxia can increase metastatic capacity and lead to resistance to chemotherapy and radiotherapy. Hypoxia also leads to altered transcription and translation of a...

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主要な著者: Luoto, Kaisa R, Kumareswaran, Ramya, Bristow, Robert G
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016142/
https://ncbi.nlm.nih.gov/pubmed/24152759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-4-5
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