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Tumor hypoxia as a driving force in genetic instability
Sub-regions of hypoxia exist within all tumors and the presence of intratumoral hypoxia has an adverse impact on patient prognosis. Tumor hypoxia can increase metastatic capacity and lead to resistance to chemotherapy and radiotherapy. Hypoxia also leads to altered transcription and translation of a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016142/ https://ncbi.nlm.nih.gov/pubmed/24152759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-4-5 |
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