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Oncogene-Induced Replication Stress Drives Genome Instability and Tumorigenesis
Genomic instability plays a key role in driving cancer development. It is already found in precancerous lesions and allows the acquisition of additional cancerous features. A major source of genomic instability in early stages of tumorigenesis is DNA replication stress. Normally, origin licensing an...
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| Vydáno v: | Int J Mol Sci |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5535832/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071339 |
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