Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase

The allosteric inhibitors of integrase (termed ALLINIs) interfere with HIV replication by binding to the viral-encoded integrase (IN) protein. Surprisingly, ALLINIs interfere not with DNA integration but with viral particle assembly late during HIV replication. To investigate the ALLINI inhibitory m...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Gupta, Kushol, Turkki, Vesa, Sherrill-Mix, Scott, Hwang, Young, Eilers, Grant, Taylor, Louis, McDanal, Charlene, Wang, Ping, Temelkoff, David, Nolte, Robert T., Velthuisen, Emile, Jeffrey, Jerry, Van Duyne, Gregory D., Bushman, Frederic D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147827/
https://ncbi.nlm.nih.gov/pubmed/27935939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002584
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker