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Structural Properties of HIV Integrase·Lens Epithelium-derived Growth Factor Oligomers

Integrase (IN) is the catalytic component of the preintegration complex, a large nucleoprotein assembly critical for the integration of the retroviral genome into a host chromosome. Although partial crystal structures of human immunodeficiency virus IN alone and its complex with the integrase bindin...

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Detalhes bibliográficos
Main Authors: Gupta, Kushol, Diamond, Tracy, Hwang, Young, Bushman, Frederic, Van Duyne, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888443/
https://ncbi.nlm.nih.gov/pubmed/20406807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114413
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