Solution Conformations of Prototype Foamy Virus Integrase and its Stable Synaptic Complex with U5 Viral DNA

Using small-angle x-ray and neutron scattering (SAXS/SANS) in combination with analytical centrifugation and light scattering, we have determined the solution properties of PFV IN alone and its synaptic complex with processed U5 viral DNA and related these properties to models derived from available...

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Autors principals: Gupta, Kushol, Curtis, Joseph E., Krueger, Susan, Hwang, Young, Cherepanov, Peter, Bushman, Frederic D., Van Duyne, Gregory D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034761/
https://ncbi.nlm.nih.gov/pubmed/23000384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.023
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