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Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1
Endosomal sorting complexes required for transport (ESCRTs) are essential for ubiquitin-dependent degradation of mitogenic receptors, a process often compromised in cancer pathologies. Sorting of ubiquinated receptors via ESCRTs is controlled by the tumor suppressor phosphatase HD-PTP. The specific...
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| Publicado en: | Structure |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cell Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5145805/ https://ncbi.nlm.nih.gov/pubmed/27839950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.10.006 |
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