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Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed ubiquitously throughout the brain, where they function to regulate the excitability of neurons. The subcellular distribution of these channels in pyramidal neurons of hippocampal area CA1 is regulated by tetratricopepti...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Vis Exp
Asıl Yazarlar: Han, Ye, Lyman, Kyle A., Clutter, Matt, Schiltz, Gary E., Ismail, Quratul-Ain, Cheng, Xiangying, Luan, Chi-Hao, Chetkovich, Dane M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MyJove Corporation 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145243/
https://ncbi.nlm.nih.gov/pubmed/27911380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54540
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