Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels

Tetratricopeptide repeat (TPR) domains are ubiquitous structural motifs that mediate protein–protein interactions. For example, the TPR domains in the peroxisomal import receptor PEX5 enable binding to a range of type 1 peroxisomal targeting signal motifs. A homolog of PEX5, tetratricopeptide repeat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Lyman, Kyle A., Han, Ye, Heuermann, Robert J., Cheng, Xiangying, Kurz, Jonathan E., Lyman, Reagan E., Van Veldhoven, Paul P., Chetkovich, Dane M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Neurobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663874/
https://ncbi.nlm.nih.gov/pubmed/28887304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802256
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