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HCN channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects

Major Depressive Disorder is a prevalent psychiatric condition with limited therapeutic options beyond monoaminergic therapies. Although effective in some individuals, many patients fail to respond adequately to existing treatments and new pharmacologic targets are needed. HCN channels regulate exci...

詳細記述

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書誌詳細
出版年:Mol Psychiatry
主要な著者: Han, Ye, Heuermann, Robert J., Lyman, Kyle A., Fisher, Daniel, Ismail, Quratul-Ain, Chetkovich, Dane M.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233690/
https://ncbi.nlm.nih.gov/pubmed/27400855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.99
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