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Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed ubiquitously throughout the brain, where they function to regulate the excitability of neurons. The subcellular distribution of these channels in pyramidal neurons of hippocampal area CA1 is regulated by tetratricopepti...

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書目詳細資料
發表在:J Vis Exp
Main Authors: Han, Ye, Lyman, Kyle A., Clutter, Matt, Schiltz, Gary E., Ismail, Quratul-Ain, Cheng, Xiangying, Luan, Chi-Hao, Chetkovich, Dane M.
格式: Artigo
語言:Inglês
出版: MyJove Corporation 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145243/
https://ncbi.nlm.nih.gov/pubmed/27911380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54540
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