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Identification of small molecule inhibitors of hyperpolarization-activated cyclic nucleotide gated channels
Hyperpolarization-activated cyclic nucleotide gated (HCN) channels function in the brain to limit neuronal excitability. Limiting the activity of these channels has been proposed as a therapy for Major Depressive Disorder, but the critical role of HCN channels in cardiac pacemaking has limited effor...
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| 發表在: | J Biomol Screen |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755285/ https://ncbi.nlm.nih.gov/pubmed/26045196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115589590 |
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