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Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in Epilepsy

Epilepsy is a common brain disorder characterized by the occurrence of spontaneous seizures. These bursts of synchronous firing arise from abnormalities of neuronal networks. Excitability of individual neurons and neuronal networks is largely governed by ion channels and, indeed, abnormalities of a...

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Bibliographic Details
Published in:Cold Spring Harb Perspect Med
Main Authors: Brennan, Gary P., Baram, Tallie Z., Poolos, Nicholas P.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772079/
https://ncbi.nlm.nih.gov/pubmed/26931806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a022384
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