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Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in Epilepsy

Epilepsy is a common brain disorder characterized by the occurrence of spontaneous seizures. These bursts of synchronous firing arise from abnormalities of neuronal networks. Excitability of individual neurons and neuronal networks is largely governed by ion channels and, indeed, abnormalities of a...

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Pubblicato in:Cold Spring Harb Perspect Med
Autori principali: Brennan, Gary P., Baram, Tallie Z., Poolos, Nicholas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772079/
https://ncbi.nlm.nih.gov/pubmed/26931806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a022384
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