Cargando...

Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are expressed ubiquitously throughout the brain, where they function to regulate the excitability of neurons. The subcellular distribution of these channels in pyramidal neurons of hippocampal area CA1 is regulated by tetratricopepti...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Han, Ye, Lyman, Kyle A., Clutter, Matt, Schiltz, Gary E., Ismail, Quratul-Ain, Cheng, Xiangying, Luan, Chi-Hao, Chetkovich, Dane M.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145243/
https://ncbi.nlm.nih.gov/pubmed/27911380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54540
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!