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Toward the synthesis of the carbacylic ansa antibiotic kendomycin

The convergent synthesis of a benzofuran analog of the carbacyclic ansa compound kendomycin has been achieved by assembling three major fragments by means of epoxide opening and directed ortho lithiation. The crucial tetrahydropyran ring was formed by a highly stereoselective cationic cyclization. A...

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Detalhes bibliográficos
Main Authors: Mulzer, Johann, Pichlmair, Stefan, Green, Martin P., Marques, Maria M. B., Martin, Harry J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514420/
https://ncbi.nlm.nih.gov/pubmed/15277689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401503101
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